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Tackling treatment uncertainties together

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Welcome to the James Lind Alliance website

The James Lind Alliance (JLA) is a non-profit making initiative which was established in 2004. It brings patients, carers and clinicians together to identify and prioritise the Top 10 uncertainties, or 'unanswered questions', about the effects of treatments that they agree are most important.

The aim of this is to help ensure that those who fund health research are aware of what matters to both patients and clinicians. The JLA method, described in the JLA Guidebook, is designed to lead to changes in the way research funding is granted, with a view to raising awareness of research questions which are of direct relevance and potential benefit to patients and the clinicians who treat them.

Focusing on specific conditions or areas of healthcare, the JLA facilitates Priority Setting Partnerships (PSPs) which:

  • bring patient, carer and clinician groups together on an equal footing
  • identify treatment uncertainties (questions about treatments which cannot be answered by existing research) which are important to both groups
  • work with both groups jointly to prioritise the uncertainties
  • produce a Top 10 list of jointly agreed uncertainties as research questions to be presented to research funders.

Since 1 April 2013, the secretariat of the JLA has been hosted by the National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre (NETSCC). This work includes recruiting and training JLA Advisers, coordinating PSPs, looking after central JLA communications and liaising with other parts of the National Institute for Health Research (NIHR).

JLA PSPs are characterised by following the method set out in the JLA Guidebook and are facilitated by one of a small team of NETSCC-approved JLA Advisers.





Working in Partnership with NHS National Institute for Health Research

Copyright 2015 James Lind Alliance